Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979525 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1POLBADORA3ADORA1 | |
| SCHEMBL30393698 | 0.88 | ADORA3 (0.48) | KDM4EALDH1A1POLBADORA3ADORA1 | |
| SCHEMBL22988213 | 0.88 | ADORA3 (0.48) | KDM4EALDH1A1POLBADORA3ADORA1 | |
| SCHEMBL22987710 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1POLBADORA3ADORA1 | |
| SCHEMBL30393525 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1POLBADORA3ADORA1 | |
| SCHEMBL22988185 | 0.87 | ADORA3 (0.56) | KDM4EALDH1A1POLBADORA3ADORA1 | |
| SCHEMBL22988147 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1POLBADORA3ADORA1 | |
| SCHEMBL22987552 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1POLBADORA3ADORA1 | |
| SCHEMBL22987426 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1POLBADORA3ADORA1 | |
| SCHEMBL22987462 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1POLBADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |