Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979305 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1POLBADORA3XDH | |
| SCHEMBL29646381 | 0.86 | XDH (0.49) | KDM4EALDH1A1POLBADORA3XDH | |
| SCHEMBL22979184 | 0.86 | XDH (0.49) | KDM4EALDH1A1POLBADORA3XDH | |
| SCHEMBL22987563 | 0.86 | XDH (0.49) | KDM4EALDH1A1POLBADORA3XDH | |
| SCHEMBL22987444 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1POLBADORA3XDH | |
| SCHEMBL22987423 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1POLBADORA3XDH | |
| SCHEMBL22987784 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1POLBADORA3XDH | |
| SCHEMBL25118769 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1POLBADORA3XDH | |
| SCHEMBL29646478 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1POLBADORA3XDH | |
| SCHEMBL22987976 | 0.81 | KDM4E (0.65) | KDM4EALDH1A1POLBADORA3XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |