Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979475 | 1.00 | ADORA3 (0.64) | ADORA3ADORA1MAPTRXFP1TP53 | |
| SCHEMBL22979023 | 0.90 | ADORA3 (0.69) | ADORA3ADORA1MAPTTP53POLB | |
| SCHEMBL29646414 | 0.90 | ADORA3 (0.69) | ADORA3ADORA1MAPTTP53POLB | |
| SCHEMBL22979578 | 0.89 | ADORA3 (0.64) | ADORA3ADORA1MAPTADORA2AHTT | |
| SCHEMBL29646432 | 0.89 | ADORA3 (0.64) | ADORA3ADORA1MAPTADORA2AHTT | |
| SCHEMBL29646319 | 0.86 | ADORA3 (0.61) | ADORA3ADORA1MAPTRXFP1TP53 | |
| SCHEMBL22979754 | 0.86 | ADORA3 (0.61) | ADORA3ADORA1MAPTRXFP1TP53 | |
| SCHEMBL22979306 | 0.85 | ADORA3 (0.65) | ADORA3ADORA1MAPTADORA2APOLB | |
| SCHEMBL22987509 | 0.85 | ADORA3 (0.53) | ADORA3ADORA1MAPTADORA2APOLB | |
| SCHEMBL22980034 | 0.85 | RXFP1 (0.61) | ADORA3ADORA1MAPTRXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |