SCHEMBL2964689

SCHEMBL2964689

CC1Cc2c(Sc3cccc4c3CC(C)C4=O)cccc2C1=O

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.64
METAP1 P53582 1/20 0.35
CYP19A1 P11511 2/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2A1 P68400 1/20 0.33
KDM4E B2RXH2 1/20 0.32
NSD2 O96028 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
TSHR P16473 1/20 0.32
STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2905609 0.80 ACHE (0.66) ACHECYP19A1CSNK2A2CSNK2A1
SCHEMBL6472550 0.80 ACHE (0.66) ACHEMETAP1CYP19A1MAPK1
SCHEMBL6936179 0.78 ACHE (1.00) ACHE
SCHEMBL30666460 0.78 ACHE (1.00) ACHE
SCHEMBL13115609 0.78 ACHE (0.68) ACHECYP19A1MAPTMAPK1TSHR
SCHEMBL1453411 0.76 ACHE (0.66) ACHEMAPTTSHR
SCHEMBL5953174 0.76 ACHE (0.67) ACHEMETAP1CYP19A1CSNK2A2CSNK2A1
SCHEMBL1453605 0.76 ACHE (0.66) ACHEMETAP1CYP19A1CSNK2A2CSNK2A1
SCHEMBL29980139 0.76 ACHE (0.66) ACHEMETAP1CYP19A1CSNK2A2CSNK2A1
SCHEMBL13905614 0.76 ACHE (0.66) ACHEMETAP1CYP19A1CSNK2A2CSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 ACHE 2031/4885METAP1 1352/4885CYP19A1 2555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.