SCHEMBL29647854

SCHEMBL29647854

c1ccc(-n2c(-c3cccc(-c4cccc5c4sc4ccccc45)c3)nc3ccccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
ALOX5 P09917 1/20 0.45
HDAC1 Q13547 3/20 0.44
HDAC8 Q9BY41 3/20 0.44
HDAC6 Q9UBN7 3/20 0.44
RECQL P46063 1/20 0.44
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
GAA P10253 1/20 0.40
PTGER4 P35408 1/20 0.38
PRKACA P17612 1/20 0.38
RPS6KB1 P23443 1/20 0.38
GSK3B P49841 1/20 0.38
ROCK1 Q13464 1/20 0.38
GRIA1 P42261 1/20 0.38
CACNG8 Q8WXS5 1/20 0.38
CACNG2 Q9Y698 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL461927 1.00 ESR1 (0.46) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL29362982 1.00 ESR1 (0.46) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL15446534 0.96 ESR1 (0.44) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL12349724 0.96 ESR2 (0.47) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL12567999 0.94 ESR2 (0.44) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL12349437 0.93 ESR1 (0.44) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL12568024 0.92 ESR1 (0.49) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL430153 0.91 ESR1 (0.48) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL30350267 0.91 ESR1 (0.48) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL15446586 0.90 ESR1 (0.44) ESR1ESR2ALOX5HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022090863-A1 ORGANIC COMPOUND, CARRIER TRANSPORT MATERIAL, HOST MATERIAL, LIGHT EMITTING DEVICE, LIGHT EMITTING APPARATUS, ELECTRONIC EQUIPMENT, AND LIGHTING APPARATUS 株式会社半導体エネルギー研究所 2022-05-05 WO disclosed