SCHEMBL461927

SCHEMBL461927

c1ccc(-n2c(-c3cccc(-c4cccc5c4sc4ccccc45)c3)nc3ccccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
ALOX5 P09917 1/20 0.45
HDAC1 Q13547 3/20 0.44
HDAC8 Q9BY41 3/20 0.44
HDAC6 Q9UBN7 3/20 0.44
RECQL P46063 1/20 0.44
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
GAA P10253 1/20 0.40
PTGER4 P35408 1/20 0.38
PRKACA P17612 1/20 0.38
RPS6KB1 P23443 1/20 0.38
GSK3B P49841 1/20 0.38
ROCK1 Q13464 1/20 0.38
GRIA1 P42261 1/20 0.38
CACNG8 Q8WXS5 1/20 0.38
CACNG2 Q9Y698 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362982 1.00 ESR1 (0.46) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL29647854 1.00 ESR1 (0.46) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL15446534 0.96 ESR1 (0.44) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL12349724 0.96 ESR2 (0.47) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL12567999 0.94 ESR2 (0.44) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL12349437 0.93 ESR1 (0.44) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL12568024 0.92 ESR1 (0.49) ESR1ESR2HDAC1HDAC8HDAC6
SCHEMBL430153 0.91 ESR1 (0.48) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL30350267 0.91 ESR1 (0.48) ESR1ESR2ALOX5HDAC1HDAC8
SCHEMBL15446586 0.90 ESR1 (0.44) ESR1ESR2ALOX5HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146024-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Apparatus, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-05-28 US disclosed
US-12641925-B2 Light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-05-26 US disclosed
US-20260140538-A1 DISPLAY APPARATUS AND OPERATION METHOD THEREOF SEMICONDUCTOR ENERGY LABORATORY CO LTD (JP) 2026-05-21 US disclosed
US-20260143898-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-05-21 US disclosed
US-12630496-B2 Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-05-19 US disclosed
US-20260136756-A1 Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-05-14 US disclosed
US-20260136832-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-05-14 US disclosed
US-20260132134-A1 ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, THIN FILM, LIGHT-EMITTING APPARATUS, ELECTRONIC APPARATUS, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO LTD (JP) 2026-05-14 US disclosed
US-12624046-B2 Organic compound, light-emitting device, electronic device, electronic apparatus, light-emitting apparatus, and lighting apparatus SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-05-12 US disclosed
US-20260130046-A1 ORGANIC COMPOUND, ORGANIC SEMICONDUCTOR DEVICE, AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2026-05-07 US disclosed
US-20120025178-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 US disclosed
EP-2354135-A1 benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-10 EP disclosed
EP-2354135-A1 benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-10 EP disclosed
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
WO-2011052516-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-05-05 WO disclosed
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-05 US disclosed
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-05 US disclosed
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12641925-B2 Light-emitting device L1CAM, EPCAM, DCX ESR1 6/4885ESR2 44/4885ALOX5 2458/4885
US-20260140538-A1 DISPLAY APPARATUS AND OPERATION METHOD THEREOF VSIG8, STRA6, HAVCR2 ESR1 1915/4885ESR2 1517/4885ALOX5 4701/4885
US-20260143898-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device ESR1, ERG, EML4 ESR1 1/4885ESR2 8/4885ALOX5 1526/4885
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device CCNE2, CCNE1, CCNT1 ESR1 32/4885ESR2 216/4885ALOX5 1235/4885
US-12624046-B2 Organic compound, light-emitting device, electronic device, electronic apparatus, light-emitting apparatus, and lighting apparatus GTF2F1, GTF2F2, TEAD1 ESR1 993/4885ESR2 1143/4885ALOX5 3517/4885
US-20260132134-A1 ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, THIN FILM, LIGHT-EMITTING APPARATUS, ELECTRONIC APPARATUS, AND LIGHTING DEVICE CRY1, CTNNA1, CRY2 ESR1 151/4885ESR2 122/4885ALOX5 2939/4885
US-20260136756-A1 Light-Emitting Device SLC9A2, LAMP2, SLC25A13 ESR1 173/4885ESR2 118/4885ALOX5 4317/4885
US-20260136832-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device CYBA, SUN2, CYBB ESR1 229/4885ESR2 535/4885ALOX5 652/4885
US-20260146024-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Apparatus, and Lighting Device NR2E3, CCNE2, CCND3 ESR1 18/4885ESR2 19/4885ALOX5 2357/4885
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device GRK1, CDKL1, ARL1 ESR1 268/4885ESR2 1010/4885ALOX5 1359/4885
US-20120025178-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device LAGE3, CRY1, CYBA ESR1 219/4885ESR2 877/4885ALOX5 2474/4885
US-20260130046-A1 ORGANIC COMPOUND, ORGANIC SEMICONDUCTOR DEVICE, AND LIGHT-EMITTING DEVICE SCO2, RPS8, RPS19 ESR1 655/4885ESR2 110/4885ALOX5 3453/4885
US-12630496-B2 Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device CRY1, NR1I2, GNA11 ESR1 468/4885ESR2 338/4885ALOX5 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.