Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227991 | 0.97 | CA1 (0.39) | CA1CA2CA9APEX1GPR84 | |
| SCHEMBL29773964 | 0.97 | CA1 (0.39) | CA1CA2CA9APEX1GPR84 | |
| Potassium Ion SCHEMBL1815903 | 0.97 | CA1 (0.39) | CA1CA2CA9APEX1GPR84 | |
| Lithium Ion SCHEMBL225439 | 0.97 | CA1 (0.39) | CA1CA2CA9APEX1GPR84 | |
| SCHEMBL28351191 | 0.97 | CA1 (0.39) | CA1CA2CA9APEX1GPR84 | |
| Lithium Ion SCHEMBL30728603 | 0.97 | CA1 (0.39) | CA1CA2CA9APEX1GPR84 | |
| Potassium Ion SCHEMBL31028100 | 0.97 | CA1 (0.39) | CA1CA2CA9APEX1GPR84 | |
| SCHEMBL28688722 | 0.94 | APEX1 (0.38) | CA1CA2CA9APEX1GPR84 | |
| SCHEMBL28308871 | 0.90 | CA1 (0.39) | CA1CA2CA9APEX1CYP2C19 | |
| SCHEMBL6739022 | 0.88 | CA1 (0.40) | CA1CA2CA9APEX1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032707-B | Polypropylene composition with low shrinkage at wide application temperature range | 博里利斯股份公司 | 2022-03-25 | — | — | CN | disclosed |