Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.40 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28468987 | 0.98 | CA1 (0.39) | CA1CA2CA9NR1I2APEX1 | |
| SCHEMBL28138857 | 0.98 | CA1 (0.39) | CA1CA2CA9NR1I2APEX1 | |
| Lithium Ion SCHEMBL21541943 | 0.98 | CA1 (0.39) | CA1CA2CA9NR1I2APEX1 | |
| SCHEMBL27969783 | 0.98 | CA1 (0.39) | CA1CA2CA9NR1I2APEX1 | |
| SCHEMBL28308871 | 0.98 | CA1 (0.39) | CA1CA2CA9NR1I2APEX1 | |
| Water SCHEMBL27776360 | 0.97 | CA1 (0.38) | CA1CA2CA9NR1I2APEX1 | |
| SCHEMBL28137776 | 0.95 | APEX1 (0.38) | CA1CA2CA9NR1I2APEX1 | |
| SCHEMBL227991 | 0.92 | CA1 (0.39) | CA1CA2CA9NR1I2APEX1 | |
| SCHEMBL29773964 | 0.92 | CA1 (0.39) | CA1CA2CA9NR1I2APEX1 | |
| SCHEMBL28351191 | 0.88 | CA1 (0.39) | CA1CA2CA9NR1I2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444892-A | Polypropylene material and preparation method and application thereof | 金发科技股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-116425904-A | Supported Ziegler-Natta catalyst and preparation method and application thereof | 山东京博石油化工有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-115489187-B | High-strength superfine fiber shielding material and preparation method and application thereof | 河南省驼人医疗科技有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-115746725-A | High-dimensional-stability polyolefin release film and manufacturing method thereof | 浙江道明新材料有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-114752127-A | High-molecular modified material of high-cold-resistance railway sleeper | 广东特帅科技股份有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-112457639-A | Polylactic resin prepared from corn and preparation method thereof | 杨勇 | 2021-03-09 | — | — | CN | claimed |
| CN-111100381-A | Polypropylene resin for low-precipitation injection-stretch blow molding | 中国石油化工股份有限公司 | 2020-05-05 | — | — | CN | claimed |
| CN-111073102-A | Low-temperature high-permeability toughened PE shrink film material and preparation method thereof | 宁波市付枫塑业有限公司 | 2020-04-28 | — | — | CN | claimed |
| CN-116693971-B | Anti-yellowing modified composite additive for polyolefin and preparation method and application thereof | 涿州市隽诚化工有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-115678161-B | Composite nucleating agent composition and application thereof | 呈和科技股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117777201-A | Synthesis method of 2,2' -methylenebis (4, 6-di-tert-butylphenyl) phosphate hydroxyl aluminum salt | 江苏极易新材料有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117511425-B | Anti-sticking packaging adhesive film for photovoltaic module and preparation method and application thereof | 浙江祥邦永晟新能源有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-116041846-B | Low-creep ultraviolet flame-retardant material used in high-frequency vibration environment | 上海日之升科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117511425-A | Anti-sticking packaging adhesive film for photovoltaic module and preparation method and application thereof | 浙江祥邦永晟新能源有限公司 | 2024-02-06 | — | — | CN | disclosed |
| EP-0779329-B1 | Styrene-based resin composition and process for producing molding products thereof | IDEMITSU KOSAN CO (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0382064-B1 | Styrene-based resin composition and process for producing molding products thereof | IDEMITSU KOSAN CO (JP) | 1997-11-26 | — | — | EP | disclosed |
| US-5663310-A | SOLVENT ETHER, KETONE, ESTER OR ALCOHOL FOR FILMS | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0779329-A2 | Styrene-based resin composition and process for producing molding products thereof | IDEMITSU KOSAN CO., LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |
| US-5034441-A | Molding material containing an organo phosphate and a polyoxyalkylene compound with a styrene resin | IDEMITSU KOSAN CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0382064-A1 | Styrene-based resin composition and process for producing molding products thereof | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-16 | — | — | EP | disclosed |