SCHEMBL29648052

SCHEMBL29648052

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 18/20 0.71
▸ NPY1R P25929 11/20 0.71
▸ NPY5R Q15761 9/20 0.71
▸ NPY2R P49146 7/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4441700 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29770018 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30713829 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL4439081 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31710585 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL3484757 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30567513 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL4441735 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL4439114 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R
SCHEMBL3485342 1.00 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590321-B2 Methods and compositions for genetically modifying and expanding lymphocytes and regulating the activity thereof EXUMA BIOTECH CORP. (US) 2026-03-31 — — US disclosed
US-12325728-B2 Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of CD79A and CD79B EXUMA BIOTECH CORP. (US) 2025-06-10 — — US disclosed
US-20220340927-A1 METHODS AND COMPOSITIONS FOR THE MODIFICATION AND DELIVERY OF LYMPHOCYTES EXUMA BIOTECH CORP. (US) 2022-10-27 — — US disclosed
US-20220306698-A1 METHODS AND COMPOSITIONS FOR GENETICALLY MODIFYING LYMPHOCYTES TO EXPRESS POLYPEPTIDES COMPRISING THE INTRACELLULAR DOMAIN OF CD79A AND CD79B EXUMA BIOTECH CORP. (US) 2022-09-29 — — US disclosed
EP-4022035-A1 METHODS AND COMPOSITIONS FOR THE MODIFICATION AND DELIVERY OF LYMPHOCYTES EXUMA BIOTECH CORP. (US) 2022-07-06 — — EP disclosed
US-11325948-B2 Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL EXUMA BIOTECH CORP. (US) 2022-05-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590321-B2 Methods and compositions for genetically modifying and expanding lymphocytes and regulating the activity thereof CD4, PBK, CD69 NPY4R 3705/4885NPY1R 3246/4885NPY5R 3277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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