Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 18/20 | 0.71 |
| ▸ | NPY1R | P25929 | 11/20 | 0.71 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.71 |
| ▸ | NPY2R | P49146 | 7/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441700 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29770018 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30713829 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29648052 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL4439081 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31710585 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL3484757 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30567513 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL4439114 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL3485342 | 1.00 | NPY4R (0.71) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10660933-B2 | Compositions and methods for inhibition of bacterial infections in human endocervix | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2020-05-26 | — | — | US | disclosed |
| US-20180207226-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF BACTERIAL INFECTIONS IN HUMAN ENDOCERVIX | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2018-07-26 | — | — | US | disclosed |
| CN-108136211-A | For inhibiting the composition of the bacterium infection in people's endocervix and method | 马里兰大学派克分院 | 2018-06-08 | — | — | CN | disclosed |
| WO-2017075573-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF BACTERIAL INFECTIONS IN HUMAN ENDOCERVIX | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2017-05-04 | — | — | WO | disclosed |
| EP-1740601-B1 | MYOSIN LIGHT CHAIN KINASE INHIBITORS AND THEIR USE | UNIV CHICAGO (US) | 2012-12-05 | — | — | EP | disclosed |
| US-7585844-B2 | Comprising nonapeptide wherein first three amino acids and last three amino acids of sequence comprise basic amino acids, and wherein inhibitor comprises at least one D-amino acid or at least one non-hydrolyzable bond; may be used to treat intestinal diseases; infectious, ischemic, inflammatory disease | THE UNIVERSITY OF CHICAGO (US) | 2009-09-08 | — | — | US | disclosed |
| CN-1997660-A | Myosin light chain kinase inhibitors and methods of use | UNIV CHICAGO (US) | 2007-07-11 | — | — | CN | disclosed |
| US-20050261196-A1 | Myosin light chain kinase inhibitors and methods of use | THE UNIVERSITY OF CHICAGO (US) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261196-A1 | Myosin light chain kinase inhibitors and methods of use | MYLK, MYLK2, MYLK3 | NPY4R 4668/4885NPY1R 4513/4885NPY5R 4334/4885 |
| US-10660933-B2 | Compositions and methods for inhibition of bacterial infections in human endocervix | VIP, PIP4K2A, PIP4K2C | NPY4R 3278/4885NPY1R 2412/4885NPY5R 2749/4885 |
| US-20180207226-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF BACTERIAL INFECTIONS IN HUMAN ENDOCERVIX | VIP, PIP4K2A, PIP4K2C | NPY4R 3278/4885NPY1R 2412/4885NPY5R 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.