Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24501909 | 1.00 | CRBN (0.47) | CRBNBCHECNR2DDB1PDK2 | |
| SCHEMBL24501502 | 0.82 | CRBN (0.55) | CRBNDDB1 | |
| SCHEMBL29648319 | 0.82 | CRBN (0.55) | CRBNDDB1 | |
| SCHEMBL30375816 | 0.77 | DDB1 (0.50) | CRBNBCHECNR2DDB1PDK2 | |
| SCHEMBL25181330 | 0.77 | DDB1 (0.50) | CRBNBCHECNR2DDB1PDK2 | |
| SCHEMBL30805397 | 0.74 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL22276609 | 0.74 | CRBN (0.70) | CRBNDDB1 | |
| SCHEMBL24501937 | 0.72 | CRBN (0.58) | CRBNDDB1CA12CA1CA9 | |
| SCHEMBL29648334 | 0.72 | CRBN (0.58) | CRBNDDB1CA12CA1CA9 | |
| SCHEMBL29648321 | 0.72 | CRBN (0.58) | CRBNDDB1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |