SCHEMBL29648523

SCHEMBL29648523

CCCCC(=O)OCC(=O)[C@@]1(O)Cc2c(O)c3c(c(O)c2[C@H](O[C@H]2C[C@H](NCc4ccccc4)[C@@H](O)[C@@H](C)C2)C1)C(=O)c1c(OC)cccc1C3=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHN2 P52757 1/20 1.00
▸ PRKCD Q05655 1/20 1.00
▸ MEN1 O00255 6/20 0.65
▸ THRB P10828 6/20 0.65
▸ KMT2A Q03164 6/20 0.65
▸ HTT P42858 3/20 0.65
▸ LMNA P02545 2/20 0.65
▸ ABCC4 O15439 2/20 0.65
▸ ABCC2 Q92887 2/20 0.65
▸ ABCC3 O15438 1/20 0.65
▸ ABCB11 O95342 1/20 0.65
▸ HDAC1 Q13547 6/20 0.53
▸ HDAC6 Q9UBN7 6/20 0.53
▸ HDAC2 Q92769 5/20 0.53
▸ HDAC8 Q9BY41 5/20 0.53
▸ EBP Q15125 2/20 0.51
▸ DHCR7 Q9UBM7 2/20 0.51
▸ RECQL P46063 4/20 0.51
▸ BLM P54132 4/20 0.51
▸ TDP1 Q9NUW8 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16562342 0.90 CHN2 (0.81) CHN2PRKCDMEN1THRBKMT2A
SCHEMBL30139090 0.90 CHN2 (0.81) CHN2PRKCDMEN1THRBKMT2A
SCHEMBL22275557 0.84 MEN1 (0.74) CHN2PRKCDMEN1THRBKMT2A
SCHEMBL13798724 0.82 CHN2 (0.70) CHN2PRKCDMEN1THRBKMT2A
SCHEMBL1103790 0.80 MEN1 (0.67) CHN2PRKCDMEN1THRBKMT2A
SCHEMBL13798725 0.80 MEN1 (0.67) CHN2PRKCDMEN1THRBKMT2A
SCHEMBL18751205 0.79 MEN1 (0.73) CHN2PRKCDMEN1THRBKMT2A
SCHEMBL14703485 0.79 MEN1 (0.73) CHN2PRKCDMEN1THRBKMT2A
SCHEMBL14706187 0.79 MEN1 (0.73) CHN2PRKCDMEN1THRBKMT2A
SCHEMBL21026497 0.79 CHN2 (0.65) CHN2PRKCDMEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005877-A SiRNA for inhibiting expression of complement factor B and application thereof 纳肽得(青岛)生物医药有限公司 2025-05-16 — — CN claimed
US-20240366521-A1 NANOPARTICLES AND METHODS OF USE QANA THERAPEUTICS INC. 2024-11-07 — — US claimed
WO-2024155728-A1 NANOPARTICLES AND METHODS OF USE QANA THERAPEUTICS INC. (US) 2024-07-25 — — WO claimed
WO-2025109003-A1 P-CADHERIN LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-05-30 — — WO disclosed
CN-120005877-A SiRNA for inhibiting expression of complement factor B and application thereof 纳肽得(青岛)生物医药有限公司 2025-05-16 — — CN disclosed
US-20240366521-A1 NANOPARTICLES AND METHODS OF USE QANA THERAPEUTICS INC. 2024-11-07 — — US disclosed
WO-2024155728-A1 NANOPARTICLES AND METHODS OF USE QANA THERAPEUTICS INC. (US) 2024-07-25 — — WO disclosed
US-20240124889-A1 COMPOSITIONS AND METHODS FOR THE VECTORED AUGMENTATION OF PROTEIN DESTRUCTION, EXPRESSION AND/OR REGULATION VOYAGER THERAPEUTICS, INC. 2024-04-18 — — US disclosed
US-11666589-B2 Pivarubicin and benzarubicin compositions PARADOX PHARMACEUTICALS INC (US) 2023-06-06 — — US disclosed
US-20220389449-A1 COMPOSITIONS FOR THE TREATMENT OF DISEASE VOYAGER THERAPEUTICS, INC. 2022-12-08 — — US disclosed
CN-115298312-A Leucine-rich repeat kinase 2 (LRRK 2) iRNA agent compositions and methods of use thereof 阿尔尼拉姆医药品有限公司 2022-11-04 — — CN disclosed
US-20220213219-A1 Bruton's Tyrosine Kinase as Anti-Cancer Drug Target THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY 2022-07-07 — — US disclosed
US-11326182-B2 Compositions for the treatment of disease VOYAGER THERAPEUTICS, INC. (US) 2022-05-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366521-A1 NANOPARTICLES AND METHODS OF USE CD63, CLTB, CD47 CHN2 928/4885PRKCD 3858/4885MEN1 1634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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