SCHEMBL29648539

SCHEMBL29648539

COC(=O)CCC(=O)NCC(=O)OC

nearest known ligand 0.75

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.75
TSHR P16473 4/20 0.62
TET2 Q6N021 1/20 0.52
GAA P10253 1/20 0.48
LMNA P02545 4/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 5/20 0.43
HTT P42858 2/20 0.43
KMT2A Q03164 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPT P10636 1/20 0.43
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 1/20 0.43
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13286460 0.86 RECQL (0.57) RECQLTSHRGAALMNAKDM4E
SCHEMBL2754583 0.86 RECQL (0.69) RECQLTSHRTET2GAALMNA
SCHEMBL23085256 0.86 RECQL (0.83) RECQLTSHRTET2GAALMNA
SCHEMBL19448715 0.86 TSHR (0.62) RECQLTSHRTET2LMNAKDM4E
SCHEMBL13188964 0.86 RECQL (0.57) RECQLTSHRTET2GAALMNA
SCHEMBL125974 0.86 GAA (0.70) RECQLTSHRGAALMNAKDM4E
SCHEMBL810809 0.84 RECQL (0.72) RECQLTSHRTET2GAAALDH1A1
SCHEMBL13246470 0.83 RECQL (0.64) RECQLTSHRTET2GAALMNA
SCHEMBL9560019 0.82 RECQL (0.69) RECQLTSHRTET2GAAKDM4E
SCHEMBL22345240 0.82 RECQL (0.69) RECQLTSHRTET2GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4589059-A2 PROCESS FOR MICROSATELLITE INSTABILITY DETECTION Personal Genome Diagnostics, Inc. (US) 2025-07-23 EP disclosed
EP-3717520-B1 PROCESS FOR MICROSATELLITE INSTABILITY DETECTION PERSONAL GENOME DIAGNOSTICS INC (US) 2025-04-16 EP disclosed
US-20240124889-A1 COMPOSITIONS AND METHODS FOR THE VECTORED AUGMENTATION OF PROTEIN DESTRUCTION, EXPRESSION AND/OR REGULATION VOYAGER THERAPEUTICS, INC. 2024-04-18 US disclosed
CN-117744101-A Method and system for acquiring encrypted key data of converter secondary smelting process based on image recognition mode 河钢乐亭钢铁有限公司 2024-03-22 CN disclosed
US-20230160002-A1 Process for Microsatellite Instability Detection Personal Genome Diagnostics Inc. (US) 2023-05-25 US disclosed
US-11597967-B2 Process for microsatellite instability detection Personal Genome Diagnostics Inc. (US) 2023-03-07 US disclosed
US-20220389449-A1 COMPOSITIONS FOR THE TREATMENT OF DISEASE VOYAGER THERAPEUTICS, INC. 2022-12-08 US disclosed
US-11326182-B2 Compositions for the treatment of disease VOYAGER THERAPEUTICS, INC. (US) 2022-05-10 US disclosed