Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810809 | 0.84 | RECQL (0.72) | RECQLTET2GAATSHRHSD17B10 | |
| SCHEMBL29648539 | 0.82 | RECQL (0.75) | RECQLTET2GAATSHRHSD17B10 | |
| SCHEMBL5317737 | 0.82 | RECQL (0.61) | RECQLTET2GAATSHRSMN1; SMN2 | |
| SCHEMBL23135463 | 0.78 | RECQL (0.69) | RECQLTET2GAATSHRSMN1; SMN2 | |
| SCHEMBL9560019 | 0.78 | RECQL (0.69) | RECQLTET2GAATSHRSMN1; SMN2 | |
| SCHEMBL18753028 | 0.78 | RECQL (0.69) | RECQLTET2GAATSHRSMN1; SMN2 | |
| SCHEMBL23085256 | 0.78 | RECQL (0.83) | RECQLTET2GAATSHRHSD17B10 | |
| SCHEMBL2754583 | 0.78 | RECQL (0.69) | RECQLTET2GAATSHRHSD17B10 | |
| SCHEMBL22013210 | 0.78 | RECQL (0.62) | RECQLTET2GAATSHRSMN1; SMN2 | |
| SCHEMBL20885572 | 0.77 | RECQL (0.67) | RECQLTET2GAATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220142164-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-12 | — | — | US | disclosed |
| US-20220112175-A1 | PYRIDAZINES HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-14 | — | — | US | disclosed |
| US-20220104492-A1 | PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-07 | — | — | US | disclosed |
| EP-3927697-A1 | PYRIDAZINES HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-12-29 | — | — | EP | disclosed |
| EP-3923728-A1 | HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| EP-3924347-A1 | PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020165321-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020164973-A1 | PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020165310-A1 | PYRIDINIUM COMPOUNDS AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220142164-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | RECQL 1676/4885TET2 1513/4885GAA 160/4885 |
| US-20220112175-A1 | PYRIDAZINES HERBICIDAL COMPOUNDS | DDT, PLPBP, CYP4Z1 | RECQL 1358/4885TET2 1762/4885GAA 963/4885 |
| US-20220104492-A1 | PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | DDT, PNPO, PLPBP | RECQL 3267/4885TET2 1792/4885GAA 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.