SCHEMBL296486

SCHEMBL296486

CCCCNC1(c2nc(Cl)nc(Cl)n2)CC(C)(C)NC(C)(C)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296120 0.97 KMT2A (0.31) KMT2A
SCHEMBL7005271 0.77
SCHEMBL1249673 0.72 KDM4E (0.42) KMT2A
SCHEMBL8399541 0.72
SCHEMBL7560306 0.68 TSHR (0.32)
SCHEMBL28632316 0.65 TSHR (0.30)
Hexane SCHEMBL28831334 0.62 TSHR (0.53) KMT2A
SCHEMBL987508 0.61 KMT2A (0.66) KMT2A
SCHEMBL692462 0.60
SCHEMBL14696364 0.58 GRIN1 (0.68)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2112141-B1 Oligomeric sterically hindered amines and their use as polymer stabilizers 3V SIGMA SPA (IT) 2013-05-15 EP disclosed
US-8404765-B2 Sterically hindered amines and use thereof as polymer stabilizers 3V SIGMA S.P.A. (IT) 2013-03-26 US disclosed
EP-2216364-B9 Sterically hindered amines and use thereof as polymer stabilizers 3V SIGMA SPA (IT) 2012-08-15 EP disclosed
EP-2216364-B1 Sterically hindered amines and use thereof as polymer stabilizers 3V SIGMA SPA (IT) 2012-03-14 EP disclosed
US-8003718-B2 Oligomeric sterically hindered amines and their use as polymer stabilisers 3V SIGMA S.P.A. (IT) 2011-08-23 US disclosed
US-20100204371-A1 STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS 3V SIGMA S.P.A. (IT) 2010-08-12 US disclosed
EP-2216364-A1 Sterically hindered amines and use thereof as polymer stabilizers 3V SIGMA S.p.A (IT) 2010-08-11 EP disclosed
US-20090270536-A1 OLIGOMERIC STERICALLY HINDERED AMINES AND THEIR USE AS POLYMER STABILISERS 3V SIGMA S.P.A. (IT) 2009-10-29 US disclosed
EP-2112141-A1 Oligomeric sterically hindered amines and their use as polymer stabilizers 3V SIGMA S.p.A (IT) 2009-10-28 EP disclosed
US-5972248-A Stabilizers based on 1-aza-2,2,6,6 tetramethybicyclo [3.1.0]hexane CLARIANT GMBH (DE) 1999-10-26 US disclosed
US-5919933-A PHOTOSTABILITY, OXIDATION RESISTANCE, RADIATION RESISTANCE, HEAT RESISTANCE CLARIANT GMBH (DE) 1999-07-06 US disclosed
EP-0912514-A1 NOVEL STERICALLY HINDERED PIPERIDINE DERIVATIVES ACTING AS LIGHT STABILISERS FOR POLYMERS Clariant GmbH (DE) 1999-05-06 EP disclosed
US-5856385-A CONTAINING DIBENZYLIDENESORBITOL HOECHST AKTIENGESELLSCHAFT (DE) 1999-01-05 US disclosed
EP-0835875-A1 Stabilizers derived from 1-aza-2,2,6,6-tetramethylbicyclo(3.1.0)hexane Clariant GmbH (DE) 1998-04-15 EP disclosed
EP-0822221-A2 Novel light stabilisers based on sterically hindered amines Clariant GmbH (DE) 1998-02-04 EP disclosed
WO-1997042171-A1 NOVEL STERICALLY HINDERED PIPERIDINE DERIVATIVES ACTING AS LIGHT STABILISERS FOR POLYMERS CLARIANT GMBH (DE) 1997-11-13 WO disclosed
EP-0801102-A2 Additive mixture having nucleating action for synthetic resin matters HOECHST AKTIENGESELLSCHAFT (DE) 1997-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204371-A1 STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS CBR3, SIGMAR1, NPSR1 KMT2A 3893/4885
US-20090270536-A1 OLIGOMERIC STERICALLY HINDERED AMINES AND THEIR USE AS POLYMER STABILISERS PCBP1, PARG, PARN KMT2A 4112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.