Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979590 | 1.00 | MKNK1 (0.36) | MKNK1MKNK2MAPTADORA2AADORA1 | |
| SCHEMBL29648888 | 1.00 | MKNK1 (0.36) | MKNK1MKNK2MAPTADORA2AADORA1 | |
| SCHEMBL22988022 | 1.00 | MKNK1 (0.36) | MKNK1MKNK2MAPTADORA2AADORA1 | |
| SCHEMBL22979138 | 0.98 | MAPT (0.36) | MKNK1MKNK2MAPTFPR2SCN9A | |
| SCHEMBL29645587 | 0.98 | MAPT (0.36) | MKNK1MKNK2MAPTFPR2SCN9A | |
| SCHEMBL29648688 | 0.95 | MKNK1 (0.35) | MKNK1MKNK2MAPTADORA2AADORA1 | |
| SCHEMBL22979155 | 0.95 | MKNK1 (0.35) | MKNK1MKNK2MAPTADORA2AADORA1 | |
| SCHEMBL29648646 | 0.95 | MKNK1 (0.35) | MKNK1MKNK2MAPTADORA2AADORA1 | |
| SCHEMBL22979255 | 0.95 | MKNK1 (0.35) | MKNK1MKNK2MAPTADORA2AADORA1 | |
| SCHEMBL22980806 | 0.95 | MAPT (0.37) | MAPTFPR2SCN9AADORA3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |