Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979155 | 1.00 | MKNK1 (0.35) | MKNK1MKNK2MAPTSCN9AFPR2 | |
| SCHEMBL29648688 | 1.00 | MKNK1 (0.35) | MKNK1MKNK2MAPTSCN9AFPR2 | |
| SCHEMBL22979255 | 1.00 | MKNK1 (0.35) | MKNK1MKNK2MAPTSCN9AFPR2 | |
| SCHEMBL22979398 | 0.98 | MAPT (0.35) | MAPTSCN9AFPR2MGLLHCRTR1 | |
| SCHEMBL29645450 | 0.98 | MAPT (0.35) | MAPTSCN9AFPR2MGLLHCRTR1 | |
| SCHEMBL22988022 | 0.95 | MKNK1 (0.36) | MKNK1MKNK2MAPTSCN9AFPR2 | |
| SCHEMBL22979590 | 0.95 | MKNK1 (0.36) | MKNK1MKNK2MAPTSCN9AFPR2 | |
| SCHEMBL29648620 | 0.95 | MKNK1 (0.36) | MKNK1MKNK2MAPTSCN9AFPR2 | |
| SCHEMBL29648888 | 0.95 | MKNK1 (0.36) | MKNK1MKNK2MAPTSCN9AFPR2 | |
| SCHEMBL22979487 | 0.95 | SCN9A (0.37) | MAPTSCN9AFPR2MGLLHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |