Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979704 | 1.00 | ADORA2A (0.35) | ADORA2AADORA1ALOX5APFEN1LRRK2 | |
| SCHEMBL22979719 | 0.92 | ADORA2A (0.36) | ADORA2AADORA1ALOX5APFEN1ADORA3 | |
| SCHEMBL29646119 | 0.92 | ADORA2A (0.36) | ADORA2AADORA1ALOX5APFEN1ADORA3 | |
| SCHEMBL29645784 | 0.90 | AURKB (0.32) | JAK2JAK1TYK2JAK3BRD4 | |
| SCHEMBL22979234 | 0.90 | AURKB (0.32) | JAK2JAK1TYK2JAK3BRD4 | |
| SCHEMBL22979396 | 0.89 | ADORA2A (0.34) | ADORA2AADORA1LRRK2ADORA3ADORA2B | |
| SCHEMBL22988431 | 0.89 | ADORA2A (0.34) | ADORA2AADORA1ALOX5APFEN1LRRK2 | |
| SCHEMBL22979811 | 0.89 | ADORA2A (0.34) | ADORA2AADORA1LRRK2ADORA3ADORA2B | |
| SCHEMBL22988474 | 0.89 | ADORA2A (0.34) | ADORA2AADORA1LRRK2ADORA3ADORA2B | |
| SCHEMBL22979193 | 0.87 | ADORA2A (0.34) | ADORA2AADORA1LRRK2ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |