Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 2/20 | 0.30 |
| ▸ | SYK | P43405 | 2/20 | 0.30 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979234 | 1.00 | AURKB (0.32) | AURKBAURKAPDPK1RPS6KB1JAK2 | |
| SCHEMBL29645870 | 0.92 | ADORA3 (0.33) | — | |
| SCHEMBL22979421 | 0.92 | ADORA3 (0.33) | — | |
| SCHEMBL29648722 | 0.90 | ADORA2A (0.35) | JAK2JAK1TYK2JAK3BRD4 | |
| SCHEMBL22979704 | 0.90 | ADORA2A (0.35) | JAK2JAK1TYK2JAK3BRD4 | |
| SCHEMBL22988125 | 0.89 | AURKB (0.33) | AURKBAURKAPDPK1RPS6KB1JAK2 | |
| SCHEMBL22988234 | 0.89 | AURKB (0.33) | AURKBAURKAPDPK1RPS6KB1JAK2 | |
| SCHEMBL22979336 | 0.89 | JAK2 (0.34) | AURKBAURKAPDPK1RPS6KB1JAK2 | |
| SCHEMBL29645907 | 0.89 | JAK2 (0.34) | AURKBAURKAPDPK1RPS6KB1JAK2 | |
| SCHEMBL22988286 | 0.89 | AURKB (0.33) | AURKBAURKAPDPK1RPS6KB1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |