Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22980877 | 1.00 | ADORA2A (0.38) | ADORA2AADORA1ADORA3ADORA2BMKNK1 | |
| SCHEMBL29645736 | 0.91 | ADORA3 (0.38) | ADORA2AADORA1ADORA3ADORA2BMKNK1 | |
| SCHEMBL22979233 | 0.91 | ADORA3 (0.38) | ADORA2AADORA1ADORA3ADORA2BMKNK1 | |
| SCHEMBL22979849 | 0.90 | ADORA2A (0.34) | ADORA2AADORA1ADORA3ADORA2BMKNK1 | |
| SCHEMBL29648773 | 0.90 | ADORA2A (0.34) | ADORA2AADORA1ADORA3ADORA2BMKNK1 | |
| SCHEMBL22979399 | 0.89 | BRD4 (0.39) | ADORA2AADORA1ADORA3ADORA2BBRD4 | |
| SCHEMBL25119048 | 0.89 | ADORA3 (0.35) | ADORA2AADORA1ADORA3ADORA2BBRD4 | |
| SCHEMBL22980246 | 0.87 | ADORA2A (0.41) | ADORA2AADORA1ADORA3ADORA2BMKNK1 | |
| SCHEMBL22980138 | 0.86 | ADORA2A (0.37) | ADORA2AADORA1ADORA3ADORA2BMKNK1 | |
| SCHEMBL29645871 | 0.86 | ADORA2A (0.37) | ADORA2AADORA1ADORA3ADORA2BMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |