Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979112 | 0.96 | MAPT (0.49) | MAPTSMN1; SMN2THRBTSHRALDH1A1 | |
| SCHEMBL29646395 | 0.96 | MAPT (0.49) | MAPTSMN1; SMN2THRBTSHRALDH1A1 | |
| SCHEMBL29648930 | 0.93 | MAPT (0.45) | MAPTSMN1; SMN2THRBALDH1A1LMNA | |
| SCHEMBL22979870 | 0.89 | MAPT (0.48) | MAPTSMN1; SMN2THRBALDH1A1LMNA | |
| SCHEMBL29646384 | 0.89 | MAPT (0.48) | MAPTSMN1; SMN2THRBALDH1A1LMNA | |
| SCHEMBL22988038 | 0.89 | MAPT (0.42) | MAPTSMN1; SMN2THRBTSHRALDH1A1 | |
| SCHEMBL22988118 | 0.88 | MAPT (0.43) | MAPTSMN1; SMN2THRBTP53GAA | |
| SCHEMBL29646438 | 0.88 | MAPT (0.43) | MAPTSMN1; SMN2THRBTP53GAA | |
| SCHEMBL29648986 | 0.88 | MAPT (0.43) | MAPTSMN1; SMN2THRBTP53GAA | |
| SCHEMBL22988052 | 0.88 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |