Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 19/20 | 0.59 |
| ▸ | TDO2 | P48775 | 16/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19044189 | 1.00 | IDO1 (0.59) | IDO1TDO2CYP3A4 | |
| SCHEMBL19044240 | 0.90 | IDO1 (0.54) | IDO1TDO2CYP3A4 | |
| SCHEMBL19044422 | 0.88 | IDO1 (0.61) | IDO1TDO2CYP3A4 | |
| SCHEMBL19044219 | 0.85 | IDO1 (0.51) | IDO1TDO2CYP3A4 | |
| SCHEMBL29945343 | 0.85 | IDO1 (0.51) | IDO1TDO2CYP3A4 | |
| SCHEMBL19029707 | 0.80 | IDO1 (0.56) | IDO1TDO2CYP3A4 | |
| SCHEMBL29945511 | 0.80 | IDO1 (0.56) | IDO1TDO2CYP3A4 | |
| SCHEMBL19043962 | 0.79 | IDO1 (0.61) | IDO1TDO2CYP3A4 | |
| SCHEMBL19043963 | 0.79 | IDO1 (0.61) | IDO1TDO2CYP3A4 | |
| SCHEMBL29649312 | 0.79 | IDO1 (0.61) | IDO1TDO2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306635-A1 | TDO2 Inhibitors | GENENTECH, INC. | 2022-09-29 | — | — | US | disclosed |
| CN-110072864-B | TDO2 inhibitors | 基因泰克公司 | 2022-05-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306635-A1 | TDO2 Inhibitors | TDO2, IDO2, IDO1 | IDO1 3/4885TDO2 1/4885CYP3A4 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.