Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649439 | 0.88 | MAPK1 (0.39) | SSTR3SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL26024799 | 0.87 | SSTR3 (0.47) | SSTR3SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL29649482 | 0.87 | LTA4H (0.41) | — | |
| SCHEMBL26015644 | 0.85 | SSTR3 (0.47) | SSTR3SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL29649613 | 0.84 | PTPN1 (0.42) | SSTR3SIRT2SIRT1 | |
| SCHEMBL31677997 | 0.83 | GNPAT (0.47) | OPRK1 | |
| SCHEMBL12476215 | 0.83 | HDAC8 (0.44) | SSTR3SIRT1 | |
| SCHEMBL12476216 | 0.83 | HDAC8 (0.44) | SSTR3SIRT1 | |
| SCHEMBL12683176 | 0.83 | HDAC8 (0.44) | SSTR3SIRT1 | |
| SCHEMBL29649562 | 0.82 | SIRT2 (0.40) | SIRT2SIRT1SIRT3SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237008-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | Elucida Oncology, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093800-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. (US) | 2022-05-05 | — | — | WO | disclosed |