Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23331416 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX2TSHRRAB9A | |
| SCHEMBL31631019 | 0.90 | EPHX2 (0.52) | SMN1; SMN2KDM4EEPHX2TSHRCASP2 | |
| SCHEMBL19752250 | 0.89 | EPHX2 (0.51) | SMN1; SMN2MEN1MAPTKMT2ASLC6A5 | |
| SCHEMBL29763934 | 0.89 | EPHX2 (0.48) | SMN1; SMN2KDM4EEPHX2 | |
| SCHEMBL14616456 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EEPHX2TSHRRAB9A | |
| SCHEMBL15503378 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EEPHX2TSHRRAB9A | |
| SCHEMBL29649487 | 0.87 | MEN1 (0.54) | MEN1MAPTKMT2ASLC6A5KDM4E | |
| SCHEMBL16500463 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EEPHX2TSHRRAB9A | |
| SCHEMBL31563595 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1MAPTKMT2ASLC6A5 | |
| SCHEMBL30138611 | 0.87 | TSHR (0.56) | SMN1; SMN2MEN1MAPTKMT2ASLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237008-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | Elucida Oncology, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093800-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. (US) | 2022-05-05 | — | — | WO | disclosed |