Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901240 | 0.90 | CASP2 (0.58) | MEN1MAPTKMT2ASLC6A5EPHX2 | |
| SCHEMBL15503356 | 0.88 | EPHX2 (0.64) | MEN1MAPTKMT2ASLC6A5EPHX2 | |
| SCHEMBL29649591 | 0.87 | SMN1; SMN2 (0.50) | MEN1MAPTKMT2ASLC6A5EPHX2 | |
| SCHEMBL11912076 | 0.87 | CASP2 (0.66) | EPHX2CASP2NAAAFAAHTSHR | |
| SCHEMBL11226598 | 0.86 | EPHX2 (0.66) | MEN1MAPTKMT2ASLC6A5EPHX2 | |
| SCHEMBL8251628 | 0.85 | CASP2 (0.63) | EPHX2CASP2NAAAFAAHCNR1 | |
| SCHEMBL19977979 | 0.85 | CASP2 (0.53) | CASP2NAAAFAAHTSHRRECQL | |
| SCHEMBL25574266 | 0.85 | CASP2 (0.63) | EPHX2CASP2NAAAFAAHTSHR | |
| SCHEMBL22562632 | 0.84 | EPHX2 (0.60) | MEN1MAPTKMT2ASLC6A5EPHX2 | |
| SCHEMBL14118056 | 0.84 | EPHX2 (0.60) | MEN1MAPTKMT2ASLC6A5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237008-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | Elucida Oncology, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093800-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. (US) | 2022-05-05 | — | — | WO | disclosed |