Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25362791 | 1.00 | MAOB (0.50) | MAOBMAOAABCG2KMT2AMEN1 | |
| SCHEMBL14270131 | 0.92 | MAOB (0.55) | MAOBMAOAKMT2AMEN1ALDH1A1 | |
| SCHEMBL13554747 | 0.88 | KMT2A (0.56) | ABCG2KMT2A | |
| SCHEMBL20682706 | 0.88 | KMT2A (0.56) | ABCG2KMT2A | |
| SCHEMBL13554687 | 0.88 | KMT2A (0.56) | ABCG2KMT2A | |
| SCHEMBL13554738 | 0.88 | ABCG2 (0.55) | ABCG2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL14649336 | 0.88 | ABCG2 (0.55) | ABCG2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL24395286 | 0.84 | L3MBTL1 (0.57) | MAOBABCG2LMNAMAPTALDH1A1 | |
| SCHEMBL24395275 | 0.84 | L3MBTL1 (0.57) | MAOBABCG2LMNAMAPTALDH1A1 | |
| SCHEMBL5974513 | 0.82 | MAOB (0.68) | MAOBMAOAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237008-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | Elucida Oncology, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093800-A2 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. (US) | 2022-05-05 | — | — | WO | disclosed |