Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.70 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.57 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.53 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.53 |
| ▸ | GLP1R | P43220 | 1/20 | 0.53 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010599 | 0.94 | AGTR1 (0.62) | C5AR1AGTR1AGTR2NTSR2NTSR1 | |
| SCHEMBL9010604 | 0.94 | AGTR1 (0.62) | C5AR1AGTR1AGTR2NTSR2NTSR1 | |
| SCHEMBL29649735 | 0.94 | AGTR1 (0.62) | C5AR1AGTR1AGTR2NTSR2NTSR1 | |
| Acetic Acid SCHEMBL29619795 | 0.93 | AGTR1 (0.61) | C5AR1AGTR1AGTR2NTSR2NTSR1 | |
| SCHEMBL8741230 | 0.92 | C5AR1 (0.59) | C5AR1AGTR1AGTR2NTSR2NTSR1 | |
| SCHEMBL29976843 | 0.91 | C5AR1 (0.58) | C5AR1AGTR1AGTR2NTSR2NTSR1 | |
| SCHEMBL29619803 | 0.91 | C5AR1 (0.65) | C5AR1AGTR1AGTR2NTSR2NTSR1 | |
| SCHEMBL29976469 | 0.91 | C5AR1 (0.65) | C5AR1AGTR1AGTR2NTSR2NTSR1 | |
| SCHEMBL30832366 | 0.90 | C5AR1 (0.62) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL29976356 | 0.90 | C5AR1 (0.57) | C5AR1AGTR1AGTR2NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11331368-B2 | Angiotensin receptor agonists and uses thereof | MONASH UNIVERSITY (AU) | 2022-05-17 | — | — | US | disclosed |