Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 17/20 | 0.49 |
| ▸ | LOX | P28300 | 11/20 | 0.49 |
| ▸ | LOXL3 | P58215 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24493356 | 1.00 | LOXL2 (0.49) | LOXL2LOXLOXL3CYP1A2CYP3A4 | |
| SCHEMBL24493584 | 0.80 | HCRTR2 (0.39) | CYP2D6 | |
| SCHEMBL30578250 | 0.79 | LOXL2 (0.51) | LOXL2LOXLOXL3 | |
| SCHEMBL429671 | 0.79 | LOXL2 (0.51) | LOXL2LOXLOXL3 | |
| SCHEMBL30578218 | 0.78 | KDM2B (0.42) | — | |
| SCHEMBL27096107 | 0.76 | F12 (0.36) | — | |
| SCHEMBL27095833 | 0.76 | MRGPRX1 (0.46) | — | |
| SCHEMBL24493358 | 0.74 | LOXL2 (0.46) | LOXL2LOXLOXL3CYP1A2CYP3A4 | |
| SCHEMBL445278 | 0.73 | LOXL2 (0.50) | LOXL2LOXLOXL3CYP1A2CYP3A4 | |
| SCHEMBL4933505 | 0.72 | LOXL2 (0.70) | LOXL2LOXLOXL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255900-A2 | ENZYME INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2023-10-11 | — | — | EP | disclosed |
| CN-116745278-A | Enzyme inhibitors | 卡尔维斯塔制药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022118016-A2 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2022-06-09 | — | — | WO | disclosed |