SCHEMBL29650374

SCHEMBL29650374

COc1cc(C(C)C)c(Oc2cnc(NC(C)=O)nc2N)cc1I

nearest known ligand 0.83

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 20/20 0.83
P2RX2 Q9UBL9 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3086748 1.00 P2RX3 (0.83) P2RX3P2RX2
SCHEMBL1494179 0.91 P2RX3 (0.69) P2RX3P2RX2
SCHEMBL3087024 0.91 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL3098235 0.89 P2RX3 (0.67) P2RX3P2RX2
SCHEMBL3091239 0.89 P2RX3 (0.78) P2RX3P2RX2
SCHEMBL4410783 0.89 P2RX3 (0.78) P2RX3P2RX2
SCHEMBL3101474 0.89 P2RX3 (0.78) P2RX3P2RX2
SCHEMBL14605911 0.88 P2RX3 (0.68) P2RX3P2RX2
SCHEMBL3090903 0.88 P2RX3 (0.83) P2RX3P2RX2
SCHEMBL3085036 0.88 P2RX3 (0.77) P2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114703227-A MCF-7 cell line-based constructed RAR alpha effect in-vitro screening method 中国科学院生态环境研究中心 2022-07-05 CN claimed
US-12636385-B2 Selective ligands for tau aggregates SENTONIX, INC. (US) 2026-05-26 US disclosed
US-20260070915-A1 SUBSTITUTED 7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINES AS SELECTIVE CDK2/4 INHIBITORS INCYTE CORP (US) 2026-03-12 US disclosed
US-20250218638-A1 COMMON MODE NOISE FILTER PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2025-07-03 US disclosed
CN-119676861-A Communication method, device and storage medium 展讯半导体(南京)有限公司 2025-03-21 CN disclosed
CN-119545529-A Communication method, device and storage medium 展讯半导体(南京)有限公司 2025-02-28 CN disclosed
WO-2025031316-A1 COMMUNICATION METHOD AND APPARATUS, AND STORAGE MEDIUM 展讯半导体(南京)有限公司 2025-02-13 WO disclosed
CN-119259231-A Crushing control system and method of medical waste treatment equipment 北京大白鲨环保科技有限公司 2025-01-07 CN disclosed
CN-118830038-A Common mode noise filter 松下知识产权经营株式会社 2024-10-22 CN disclosed
CN-118741745-A Communication method and related device 展讯半导体(南京)有限公司 2024-10-01 CN disclosed
US-20240084305-A1 MODULATORS OF CELL PROLIFERATION AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-03-14 US disclosed
US-11921425-B2 Hard mask-forming composition and method for manufacturing electronic component TOKYO OHKA KOGYO CO., LTD. (JP) 2024-03-05 US disclosed
WO-2023190594-A1 COMMON MODE NOISE FILTER パナソニックIPマネジメント株式会社 2023-10-05 WO disclosed
US-20230221643-A1 HARD MASK-FORMING COMPOSITION AND METHOD FOR MANUFACTURING ELECTRONIC COMPONENT TOKYO OHKA KOGYO CO LTD (JP) 2023-07-13 US disclosed
US-11650503-B2 Hard mask-forming composition and method for manufacturing electronic component TOKYO OHKA KOGYO CO., LTD. (JP) 2023-05-16 US disclosed
US-20230001008-A1 COMPOSITIONS AND METHODS FOR TARGETING CELLULAR MOLECULES KUMQUAT BIOSCIENCES INC. 2023-01-05 US disclosed
CN-114703227-A MCF-7 cell line-based constructed RAR alpha effect in-vitro screening method 中国科学院生态环境研究中心 2022-07-05 CN disclosed
CN-114703227-A MCF-7 cell line-based constructed RAR alpha effect in-vitro screening method 中国科学院生态环境研究中心 2022-07-05 CN disclosed
US-11331931-B2 Liquid droplet discharge apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2022-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230001008-A1 COMPOSITIONS AND METHODS FOR TARGETING CELLULAR MOLECULES CD2BP2, CD47, CD74 P2RX3 4435/4885P2RX2 4446/4885
US-20260070915-A1 SUBSTITUTED 7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINES AS SELECTIVE CDK2/4 INHIBITORS CDK4, CDK2, CCNC P2RX3 3938/4885P2RX2 3991/4885
US-12636385-B2 Selective ligands for tau aggregates MAPT, PSEN2, PSEN1 P2RX3 2467/4885P2RX2 2724/4885
US-20240084305-A1 MODULATORS OF CELL PROLIFERATION AND USES THEREOF MKI67, MYC, CCNK P2RX3 4562/4885P2RX2 4240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.