SCHEMBL29650565

SCHEMBL29650565

Cc1nc2cc(C(F)(F)F)c(N3CC4(C3)CN(C3CC3)C4)c(C#N)c2c(=O)n1CCOc1ccc(Cl)cc1-c1ccnc2c(C(=O)O)csc12

nearest known ligand 0.88

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ EIF4EBP1 Q13541 20/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29650546 0.93 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650447 0.90 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650545 0.89 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650516 0.89 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650422 0.88 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650599 0.88 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650493 0.87 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650424 0.86 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650531 0.86 EIF4EBP1 (1.00) EIF4EBP1
SCHEMBL29650515 0.84 EIF4EBP1 (1.00) EIF4EBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3993875-A1 METHODS OF TREATING BRAF-MUTATED CANCER CELLS EFFECTOR THERAPEUTICS, INC. (US) 2022-05-11 — — EP disclosed
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