Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.46 |
| ▸ | CBFB | Q13951 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318947 | 1.00 | PDK2 (0.57) | PDK2PDK4LMNAKMT2AMEN1 | |
| SCHEMBL2264504 | 0.78 | PDK2 (0.64) | PDK2PDK4LMNAKMT2AMEN1 | |
| SCHEMBL29237808 | 0.78 | PDK2 (0.53) | PDK2PDK4LMNAKMT2AMEN1 | |
| SCHEMBL2264508 | 0.78 | PDK2 (0.64) | PDK2PDK4LMNAKMT2AMEN1 | |
| SCHEMBL2266448 | 0.78 | PDK2 (0.64) | PDK2PDK4LMNAKMT2AMEN1 | |
| SCHEMBL25340217 | 0.76 | LMNA (0.76) | PDK2PDK4LMNAKMT2AMEN1 | |
| SCHEMBL6288766 | 0.75 | LMNA (0.61) | PDK2PDK4LMNAKMT2AMEN1 | |
| SCHEMBL29588465 | 0.75 | LMNA (0.61) | PDK2PDK4LMNAKMT2AMEN1 | |
| SCHEMBL31076274 | 0.74 | MAPT (0.49) | PDK2PDK4LMNAKMT2AMEN1 | |
| SCHEMBL25467800 | 0.74 | GSK3B (0.50) | PDK2PDK4LMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651707-A | Novel synthetic TLR4 receptor agonists | 米兰-比可卡大学 | 2024-03-05 | — | — | CN | claimed |
| CN-114555585-B | HPK1 inhibitors and uses thereof | 锐格药业公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-115605463-B | Inhibitors of receptor-interacting protein kinase I for the treatment of diseases | 德州大学系统董事会 | 2024-08-09 | — | — | CN | disclosed |
| CN-117651707-A | Novel synthetic TLR4 receptor agonists | 米兰-比可卡大学 | 2024-03-05 | — | — | CN | disclosed |
| CN-115605463-A | Inhibitors of receptor interacting protein kinase I for the treatment of diseases | 德州大学系统董事会（US） | 2023-01-13 | — | — | CN | disclosed |
| EP-4091450-A1 | 3,3-DIFLUORO-2-OXOINDOLINE DERIVATIVES USEFUL IN WEED CONTROL | Syngenta Crop Protection AG (CH) | 2022-11-23 | — | — | EP | disclosed |
| CN-114555585-A | HPK1 inhibitors and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-3994133-A1 | HPK1 INHIBITORS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2022-05-11 | — | — | EP | disclosed |