SCHEMBL29652452

SCHEMBL29652452

COc1ccc(OC)c(S(=O)(=O)Nc2noc3ccccc23)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 4/20 0.78
BRD4 O60885 1/20 0.59
KMT2A Q03164 4/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
GAA P10253 3/20 0.58
MEN1 O00255 3/20 0.58
MAPT P10636 3/20 0.58
TP53 P04637 3/20 0.58
ALDH1A1 P00352 2/20 0.58
KDM4E B2RXH2 1/20 0.58
POLB P06746 1/20 0.58
PKM P14618 1/20 0.58
HPGD P15428 1/20 0.58
ALOX15 P16050 1/20 0.58
CASP1 P29466 1/20 0.58
HTT P42858 1/20 0.58
HSD17B10 Q99714 1/20 0.58
KAT7 O95251 3/20 0.55
KAT6B Q8WYB5 2/20 0.55
KAT5 Q92993 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21609114 1.00 KAT6A (0.78) KAT6ABRD4KMT2ASMN1; SMN2GAA
SCHEMBL21609026 0.91 KAT6A (0.67) KAT6ABRD4KMT2ASMN1; SMN2GAA
SCHEMBL21641922 0.88 KAT6A (0.78) KAT6ABRD4KMT2ASMN1; SMN2GAA
SCHEMBL29652535 0.88 KAT6A (0.78) KAT6ABRD4KMT2ASMN1; SMN2GAA
SCHEMBL21609129 0.87 KAT6A (0.74) KAT6ABRD4KMT2ASMN1; SMN2MAPT
SCHEMBL29652570 0.87 KAT6A (0.74) KAT6ABRD4KMT2ASMN1; SMN2MAPT
SCHEMBL21641934 0.86 KAT6A (0.74) KAT6ABRD4KMT2AKAT7KAT6B
SCHEMBL29652517 0.86 KAT6A (0.74) KAT6ABRD4KMT2AKAT7KAT6B
SCHEMBL21641937 0.85 KAT6A (0.73) KAT6ABRD4KMT2ASMN1; SMN2ALDH1A1
SCHEMBL21641930 0.85 KAT6A (0.73) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT6A 877/4885BRD4 1909/4885KMT2A 4165/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B KAT6A 160/4885BRD4 343/4885KMT2A 890/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 KAT6A 878/4885BRD4 1913/4885KMT2A 4165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.