Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972933 | 0.89 | SLC6A2 (0.35) | TP53MAPTPOLBSLC6A2HTR2A | |
| SCHEMBL2975438 | 0.77 | ALDH1A1 (0.36) | TP53HTR2AHTR2CALDH1A1MAPK1 | |
| SCHEMBL2968608 | 0.72 | KDM1A (0.33) | HTR2CALDH1A1MAPK1 | |
| SCHEMBL1454088 | 0.71 | HTR2A (0.44) | TP53SLC6A2HTR2AHTR2CALDH1A1 | |
| SCHEMBL18270052 | 0.70 | CYP1A2 (0.40) | MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL2963789 | 0.68 | MAPK1 (0.36) | TP53MAPTALDH1A1MAPK1 | |
| SCHEMBL2973795 | 0.67 | ALDH1A1 (0.32) | SLC6A2SLC6A4ALDH1A1MAPK1 | |
| SCHEMBL2969380 | 0.66 | NPC1 (0.41) | TP53MAPTALDH1A1MAPK1 | |
| SCHEMBL2970691 | 0.66 | MEN1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL1454723 | 0.64 | HTR2A (0.39) | TP53SLC6A2HTR2AHTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | TP53 4276/4885MAPT 206/4885POLB 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.