Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24456663 | 1.00 | TAAR1 (0.46) | TAAR1SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL27592582 | 0.79 | GABRA1 (0.45) | TAAR1 | |
| SCHEMBL8407898 | 0.79 | HTR2A (0.51) | SLC6A4HTR2AHTR2CHTR2BHTR7 | |
| SCHEMBL30817990 | 0.78 | GABRA1 (0.39) | TAAR1 | |
| SCHEMBL17979977 | 0.78 | GABRA1 (0.39) | TAAR1 | |
| SCHEMBL6355831 | 0.76 | GABRA1 (0.38) | TAAR1 | |
| SCHEMBL11135816 | 0.76 | TAAR1 (0.78) | TAAR1SLC6A4HTR7SIGMAR1 | |
| SCHEMBL534488 | 0.75 | GABRA1 (0.36) | TAAR1 | |
| SCHEMBL27583 | 0.75 | GABRA1 (0.43) | TAAR1HTR2A | |
| SCHEMBL16954492 | 0.75 | GABRA1 (0.48) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109492-A1 | PYRROLOPYRIDAZINE COMPOUNDS AS KINASE INHIBITORS | GOSSAMER BIOSERVICES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |