Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 3/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797830 | 1.00 | HRH3 (0.58) | HRH3MMP13MMP2HCRTR1ALDH1A1 | |
| SCHEMBL5793342 | 0.84 | CREBBP (0.48) | HRH3ALDH1A1KDM4ERAB9AMEN1 | |
| SCHEMBL7920888 | 0.82 | ALDH1A1 (0.68) | HRH3MMP13MMP2HCRTR1ALDH1A1 | |
| SCHEMBL68923 | 0.81 | HRH3 (0.84) | HRH3MMP13MMP2HCRTR1ALDH1A1 | |
| SCHEMBL13061311 | 0.79 | CYP2A6 (0.51) | HRH3MMP13MMP2ALDH1A1RAB9A | |
| SCHEMBL16938458 | 0.79 | HRH3 (0.59) | HRH3MMP13MMP2HCRTR1ALDH1A1 | |
| SCHEMBL29654185 | 0.79 | HRH3 (0.59) | HRH3MMP13MMP2HCRTR1ALDH1A1 | |
| SCHEMBL6518479 | 0.79 | HRH3 (0.80) | HRH3MMP13MMP2HCRTR1ALDH1A1 | |
| SCHEMBL27683606 | 0.78 | HRH3 (0.58) | HRH3MMP13MMP2HCRTR1ALDH1A1 | |
| SCHEMBL27768714 | 0.78 | HRH3 (0.58) | HRH3MMP13MMP2HCRTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109485595-B | Hydrophilic group substituted indole formamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |