Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28716317 | 1.00 | KDM1A (0.70) | KDM1AMAPTGAACYP1A2CYP1A1 | |
| SCHEMBL29654005 | 0.86 | KDM1A (0.78) | KDM1AMAPTGAACYP1A2CYP1A1 | |
| SCHEMBL28707161 | 0.86 | KDM1A (0.78) | KDM1AMAPTGAACYP1A2CYP1A1 | |
| SCHEMBL28716330 | 0.85 | ALOX5 (0.52) | KDM1AMAPTGAACYP1A2CYP1A1 | |
| SCHEMBL28713943 | 0.83 | CYP1A2 (0.53) | KDM1AMAPTCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL29654077 | 0.83 | CYP1A2 (0.53) | KDM1AMAPTCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL2870272 | 0.83 | KDM1A (0.78) | KDM1AMAPTGAACYP1A2CYP1A1 | |
| SCHEMBL28717687 | 0.82 | KDM1A (0.67) | KDM1AMAPTGAACYP1A2CYP1A1 | |
| SCHEMBL2880884 | 0.77 | KDM1A (0.72) | KDM1AMAPTGAACYP1A2CYP1A1 | |
| SCHEMBL23553978 | 0.74 | CFTR (0.77) | KDM1AMAPTCYP1A2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249702-B | N-aryl- [2,4 '-dithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |