Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 4/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24525378 | 1.00 | JAK2 (0.44) | JAK2TYK2CFTRPDE3BPDE3A | |
| SCHEMBL25486953 | 0.85 | JAK2 (0.46) | JAK2TYK2L3MBTL1TSHRSLC6A4 | |
| SCHEMBL24525459 | 0.84 | JAK2 (0.43) | JAK2TYK2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL24525000 | 0.84 | CFTR (0.37) | CFTRPIK3CAABL1SRCNTRK1 | |
| SCHEMBL29654506 | 0.84 | CFTR (0.37) | CFTRPIK3CAABL1SRCNTRK1 | |
| SCHEMBL29654668 | 0.83 | CFTR (0.55) | CFTRPDE3BPDE3AL3MBTL1ALDH1A1 | |
| SCHEMBL24525019 | 0.83 | CFTR (0.55) | CFTRPDE3BPDE3AL3MBTL1ALDH1A1 | |
| SCHEMBL29476278 | 0.83 | SLC6A4 (0.49) | CFTRL3MBTL1ALDH1A1HPGDTSHR | |
| SCHEMBL23541000 | 0.83 | SLC6A4 (0.49) | CFTRL3MBTL1ALDH1A1HPGDTSHR | |
| SCHEMBL23539711 | 0.81 | ALPL (0.41) | CFTRL3MBTL1ALDH1A1TSHRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133345-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. (US) | 2022-06-23 | — | — | WO | disclosed |