SCHEMBL29655238

SCHEMBL29655238

COc1cc(OC)c(C=O)cc1Br

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
KDM4E B2RXH2 2/20 0.69
TSHR P16473 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
PRKDC P78527 1/20 0.62
ERN1 O75460 3/20 0.50
PTPN1 P18031 2/20 0.50
LMNA P02545 2/20 0.50
HPGD P15428 1/20 0.50
TNFRSF1A P19438 1/20 0.50
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
SIRT1 Q96EB6 1/20 0.44
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539323 1.00 ALDH1A1 (0.69) ALDH1A1KDM4ETSHRTDP1PRKDC
SCHEMBL2037836 0.92 PRKDC (0.74) ALDH1A1KDM4ETSHRTDP1PRKDC
SCHEMBL18270047 0.88 PRKDC (0.81) ALDH1A1KDM4ETSHRTDP1PRKDC
SCHEMBL30665931 0.88 PRKDC (0.81) ALDH1A1KDM4ETSHRTDP1PRKDC
SCHEMBL1571567 0.86 PRKDC (0.56) ALDH1A1KDM4ETSHRTDP1PRKDC
SCHEMBL13271943 0.84 ALDH1A1 (0.55) ALDH1A1KDM4ETSHRTDP1PRKDC
SCHEMBL8715769 0.84 ALDH1A1 (0.50) ALDH1A1KDM4ETSHRTDP1PRKDC
SCHEMBL20140184 0.84 ALDH1A1 (0.55) ALDH1A1KDM4ETSHRTDP1PRKDC
SCHEMBL10849623 0.84 ALDH1A1 (0.86) ALDH1A1KDM4ETSHRTDP1PRKDC
SCHEMBL2859718 0.84 PRKDC (0.58) ALDH1A1KDM4ETSHRTDP1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853652-B Sulfonium salt compound, preparation method and application thereof, and cationic UV (ultraviolet) curing adhesive 韦尔通科技股份有限公司 2023-08-29 CN disclosed
CN-111094262-B 1, 3-dioxane-4, 6-diketone compound, preparation method thereof, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2022-12-20 CN disclosed
CN-114853652-A Sulfonium salt compound, preparation method and application thereof, and cationic UV (ultraviolet) curing adhesive 韦尔通(厦门)科技股份有限公司 2022-08-05 CN disclosed
CN-109843874-B Phthalazine derivatives useful as inhibitors of PARP1, PARP2 and/or tubulin for the treatment of cancer 加利福尼亚大学董事会 2022-05-27 CN disclosed