Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | PDE5A | O76074 | 17/20 | 0.76 |
| ▸ | PDE6C | P51160 | 3/20 | 0.76 |
| ▸ | PDE1A | P54750 | 3/20 | 0.76 |
| ▸ | PDE2A | O00408 | 2/20 | 0.76 |
| ▸ | PDE9A | O76083 | 2/20 | 0.76 |
| ▸ | PDE4A | P27815 | 2/20 | 0.76 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.76 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.76 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.76 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.76 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.76 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.76 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.76 |
| ▸ | PDE6D | O43924 | 1/20 | 0.76 |
| ▸ | PDE8A | O60658 | 1/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071 | 1.00 | KMT2A (0.83) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL31202676 | 0.94 | KMT2A (0.73) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL1253 | 0.94 | KMT2A (0.73) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL6628860 | 0.92 | KMT2A (0.85) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL3313876 | 0.92 | KMT2A (0.70) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL21995693 | 0.91 | KMT2A (0.83) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL5450370 | 0.90 | KMT2A (0.71) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL1263 | 0.90 | KMT2A (0.68) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL30848678 | 0.89 | PDE5A (0.95) | KMT2AKDM4EPDE5APDE6CPDE1A | |
| SCHEMBL845 | 0.88 | PDE5A (0.68) | KMT2AKDM4EPDE5APDE6CPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166157-B | Double-acting mode soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof | 托帕杜制药公司 | 2024-08-27 | — | — | CN | disclosed |
| EP-4259634-A1 | NOVEL COMPOUNDS AS ANDROGEN RECEPTOR AND PHOSPHODIESTERASE DUAL INHIBITOR | Ildong Pharmaceutical Co., Ltd. (KR) | 2023-10-18 | — | — | EP | disclosed |
| EP-4058457-A2 | NITROGEN OXIDE-DONATING PDE-5 AND/OR PDE-6 INHIBITOR COMPOUNDS | Ildong Pharmaceutical Co., Ltd. (KR) | 2022-09-21 | — | — | EP | disclosed |
| WO-2022123310-A1 | NOVEL COMPOUNDS AS ANDROGEN RECEPTOR AND PHOSPHODIESTERASE DUAL INHIBITOR | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022096930-A2 | NITROGEN OXIDE-DONATING PDE-5 AND/OR PDE-6 INHIBITOR COMPOUNDS, AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-05-12 | — | — | WO | disclosed |