SCHEMBL29655535

SCHEMBL29655535

CC(=O)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.64
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 1/20 0.57
NPC1 O15118 1/20 0.57
MAPT P10636 1/20 0.57
PKM P14618 1/20 0.57
RAB9A P51151 1/20 0.57
SRD5A2 P31213 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.53
HPGD P15428 4/20 0.50
NPFFR2 Q9Y5X5 1/20 0.50
POLB P06746 1/20 0.48
HTT P42858 1/20 0.48
EPHX1 P07099 1/20 0.48
EPHX2 P34913 1/20 0.48
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313211 1.00 TSHR (0.64) TSHRMEN1KMT2AKDM4ENPC1
SCHEMBL8478583 1.00 TSHR (0.64) TSHRMEN1KMT2AKDM4ENPC1
Nitrogen SCHEMBL28140075 0.96 TSHR (0.59) TSHRMEN1KMT2AKDM4ENPC1
Vinyl Chloride SCHEMBL27987346 0.90 TSHR (0.53) TSHRMEN1KMT2AKDM4ENPC1
SCHEMBL30060361 0.85 TSHR (0.57) TSHRMEN1KMT2AKDM4ENPC1
Hydrochloric Acid SCHEMBL30060358 0.83 TSHR (0.55) TSHRMEN1KMT2AKDM4ENPC1
SCHEMBL11544490 0.83 SCN9A (0.58) TSHRMEN1KMT2AMAPTSRD5A2
SCHEMBL30837205 0.83 SCN9A (0.58) TSHRMEN1KMT2AMAPTSRD5A2
SCHEMBL703716 0.82 HPGD (0.53) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL11149808 0.82 MAPT (0.44) TSHRMEN1KMT2AKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-117702136-A Electrosynthesis method of 2, 5-disubstituted oxazole compound 华南理工大学 2024-03-15 CN claimed
CN-116813523-A Bisindole biphenyl compound and preparation method and application thereof 贵州医科大学 2023-09-29 CN claimed
CN-116589409-A Chemical synthesis method of chlorooxazoline amine 郑州轻工业大学 2023-08-15 CN claimed
CN-110143886-B Process for the preparation of beta-arylaminoalkols such as tulobuterol, chlorpropaline, isoadrenaline dichloride and sotalol 北京化工大学 2022-11-01 CN claimed
EP-4573086-A1 METHANOGEN INHIBITORS Agrizeronz Limited Partnership (NZ) 2025-06-25 EP disclosed
CN-119998272-A Methanogen inhibitors 阿格里泽伦茨有限合伙公司 2025-05-13 CN disclosed
CN-119462533-A I under visible light condition2Catalytic C (sp)3) Method for synthesizing quinoxaline compound by virtue of H amination reaction 桂林理工大学 2025-02-18 CN disclosed
CN-115141128-B 3-Aryl-3- (sulfanilamide) acrylic acid derivative and preparation method and application thereof 沈阳药科大学 2024-09-13 CN disclosed
CN-118546122-A Compound for targeted degradation of TEAD, preparation method and application thereof 上海交通大学 2024-08-27 CN disclosed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN disclosed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN disclosed
CN-116589409-A Chemical synthesis method of chlorooxazoline amine 郑州轻工业大学 2023-08-15 CN disclosed
CN-110143886-B Process for the preparation of beta-arylaminoalkols such as tulobuterol, chlorpropaline, isoadrenaline dichloride and sotalol 北京化工大学 2022-11-01 CN disclosed
CN-112574054-B Efficient nitriding reagent and application thereof 北京大学 2022-10-14 CN disclosed
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
CN-113444081-B Thiadiazole carboxamide compounds and application thereof 浙江大学 2022-07-05 CN disclosed
CN-109320458-B Diaryl imidazole-containing compound, preparation method and medical application thereof 中国药科大学 2022-05-31 CN disclosed
CN-113061118-B Phenazine-chalcone hybrid compound and preparation method and application thereof 株洲九派科技发展有限公司 2022-05-27 CN disclosed