Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313211 | 1.00 | TSHR (0.64) | TSHRMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL29655535 | 1.00 | TSHR (0.64) | TSHRMEN1KMT2AKDM4ENPC1 | |
| Nitrogen SCHEMBL28140075 | 0.96 | TSHR (0.59) | TSHRMEN1KMT2AKDM4ENPC1 | |
| Vinyl Chloride SCHEMBL27987346 | 0.90 | TSHR (0.53) | TSHRMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL30060361 | 0.85 | TSHR (0.57) | TSHRMEN1KMT2AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL30060358 | 0.83 | TSHR (0.55) | TSHRMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11544490 | 0.83 | SCN9A (0.58) | TSHRMEN1KMT2AMAPTSRD5A2 | |
| SCHEMBL30837205 | 0.83 | SCN9A (0.58) | TSHRMEN1KMT2AMAPTSRD5A2 | |
| SCHEMBL703716 | 0.82 | HPGD (0.53) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11149808 | 0.82 | MAPT (0.44) | TSHRMEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958920-A | ANTICONVULSANTS, ANTIISCHEMIC AGENTS, BRAIN DISORDERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-09-28 | — | — | US | disclosed |
| US-5856318-A | Nitrogen-containing cyclohetero cyclo-heteroaminoaryl derivatives for CNS disorders | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-01-05 | — | — | US | disclosed |
| US-5679679-A | NERVOUS SYSTEM DISORDERS, ANTIPSYCHOTICS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-10-21 | — | — | US | disclosed |
| US-5679673-A | ANTICERBERAL ISCHEMIA, ANTIPSYCHOTIC AND ANTICONVULSION AGENT | THE UNITED STATES OF AMERICA, REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-10-21 | — | — | US | disclosed |