Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26597391 | 1.00 | FADS1 (0.44) | FADS1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL26597428 | 1.00 | FADS1 (0.44) | FADS1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL29656234 | 1.00 | FADS1 (0.44) | FADS1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL30644709 | 1.00 | FADS1 (0.44) | FADS1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL26597465 | 0.87 | FADS1 (0.47) | FADS1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL23496445 | 0.84 | SLC10A1 (0.40) | FADS1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL20509792 | 0.82 | KMT2A (0.48) | FADS1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL20510063 | 0.82 | KMT2A (0.48) | FADS1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL20510119 | 0.81 | MAPT (0.46) | FADS1NPSR1HTTSMN1; SMN2KMT2A | |
| SCHEMBL20509859 | 0.81 | NPSR1 (0.50) | FADS1NPSR1HTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240369-A1 | TARGETED CONJUGATES COMPRISING MODIFIED SIRNA | Arbutus Biopharma Corporation (CA) | 2023-09-13 | — | — | EP | disclosed |
| CN-116472063-A | Targeted conjugates comprising modified siRNAs | 阿布特斯生物制药公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2022098990-A1 | TARGETED CONJUGATES COMPRISING MODIFIED SIRNA | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-05-12 | — | — | WO | disclosed |