Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804048 | 0.68 | EGFR (0.35) | EGFR | |
| SCHEMBL7771 | 0.68 | — | — | |
| SCHEMBL140301 | 0.67 | EGFR (0.46) | EGFR | |
| SCHEMBL29809882 | 0.67 | EGFR (0.46) | EGFR | |
| Hydrochloric Acid SCHEMBL310497 | 0.67 | EGFR (0.34) | EGFR | |
| Hydrochloric Acid SCHEMBL311767 | 0.67 | EGFR (0.34) | EGFR | |
| Ammonia Solution, Strong SCHEMBL1321548 | 0.67 | EGFR (0.34) | EGFR | |
| SCHEMBL29504717 | 0.67 | EGFR (0.43) | EGFRAURKATTKAURKBINCENP | |
| SCHEMBL29656511 | 0.67 | EGFR (0.43) | EGFRAURKATTKAURKBINCENP | |
| SCHEMBL30812401 | 0.64 | AURKA (0.34) | AURKATTKAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539245-A | Pyrimidine-fused ring derivative-containing regulator, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |