SCHEMBL29657133

SCHEMBL29657133

Cc1ccc(-n2nc3c(c2NC(=O)c2cccc(Cl)c2)CSC3)c(C)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
HSD17B10 Q99714 5/20 0.69
TSHR P16473 4/20 0.69
KDM4E B2RXH2 4/20 0.69
HTT P42858 1/20 0.68
NPSR1 Q6W5P4 2/20 0.65
POLB P06746 4/20 0.63
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
HPGD P15428 2/20 0.63
CYP3A4 P08684 3/20 0.63
CYP2C9 P11712 3/20 0.63
CYP2D6 P10635 2/20 0.63
CYP2C19 P33261 2/20 0.63
CYP1A2 P05177 1/20 0.63
ENPP2 Q13822 2/20 0.54
MAPT P10636 3/20 0.52
THRB P10828 1/20 0.52
FPR1 P21462 1/20 0.52
USP2 O75604 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29563681 0.92 HTT (0.74) ALDH1A1HSD17B10TSHRKDM4EHTT
SCHEMBL29438208 0.89 HTT (0.72) ALDH1A1HSD17B10TSHRKDM4EHTT
SCHEMBL29392969 0.89 HTT (0.75) ALDH1A1HSD17B10TSHRKDM4EHTT
SCHEMBL30556476 0.89 HSD17B10 (0.69) ALDH1A1HSD17B10TSHRKDM4EHTT
SCHEMBL30101734 0.89 HSD17B10 (0.69) ALDH1A1HSD17B10TSHRKDM4EHTT
SCHEMBL29739754 0.87 HTT (0.78) ALDH1A1HSD17B10TSHRKDM4EHTT
SCHEMBL29354241 0.87 HSD17B10 (0.67) ALDH1A1HSD17B10TSHRKDM4EHTT
SCHEMBL30277755 0.86 ALDH1A1 (0.76) ALDH1A1HSD17B10TSHRKDM4EHTT
SCHEMBL29739849 0.86 HTT (0.77) ALDH1A1HSD17B10TSHRKDM4EHTT
SCHEMBL29476099 0.86 ALDH1A1 (0.73) ALDH1A1HSD17B10TSHRKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-221224242-U Wheel testing device 本田技研工业株式会社 2024-06-25 CN disclosed
US-11963980-B2 Activated CD26-high immune cells and CD26-negative immune cells and uses thereof MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2024-04-23 US disclosed
CN-117659179-A Novel crown broad spectrum neutralizing antibody and application thereof 细胞生态海河实验室 2024-03-08 CN disclosed
WO-2023181633-A1 SWITCHING APPARATUS AND DC/DC CONVERTER ローム株式会社 2023-09-28 WO disclosed
EP-3738135-B1 BORON X-RAY WINDOW MOXTEK INC (US) 2023-06-14 EP disclosed
EP-3545345-B1 WIRE GRID POLARIZER HEAT SINK MOXTEK INC (US) 2022-11-02 EP disclosed
US-11361933-B2 Boron X-ray window MOXTEK, INC. (US) 2022-06-14 US disclosed