SCHEMBL29657259

SCHEMBL29657259

COc1ccc(N)c(-c2nc3ccccc3s2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.66
SMN1; SMN2 Q16637 6/20 0.66
KDM4E B2RXH2 5/20 0.66
RAB9A P51151 5/20 0.66
MEN1 O00255 5/20 0.66
KMT2A Q03164 5/20 0.66
TDP1 Q9NUW8 4/20 0.66
ALDH1A1 P00352 4/20 0.66
NPC1 O15118 4/20 0.66
L3MBTL1 Q9Y468 3/20 0.66
GAA P10253 3/20 0.66
PKM P14618 1/20 0.61
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60
HPGD P15428 1/20 0.59
HCRTR1 O43613 1/20 0.58
GLA P06280 1/20 0.58
TP53 P04637 2/20 0.53
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25329222 1.00 MAPT (0.66) MAPTSMN1; SMN2KDM4ERAB9AMEN1
SCHEMBL28801433 0.84 APP (0.64) MAPTSMN1; SMN2KDM4ERAB9AMEN1
SCHEMBL11755034 0.84 KDM4E (0.72) MAPTSMN1; SMN2KDM4ERAB9AMEN1
SCHEMBL5429408 0.83 MAPT (0.64) MAPTSMN1; SMN2KDM4ERAB9AMEN1
SCHEMBL30386590 0.83 MAPT (0.64) MAPTSMN1; SMN2KDM4ERAB9AMEN1
SCHEMBL5981201 0.82 MAPT (0.71) MAPTSMN1; SMN2KDM4ERAB9AMEN1
SCHEMBL15454599 0.82 MAPT (0.72) MAPTSMN1; SMN2KDM4ERAB9AMEN1
SCHEMBL29478092 0.81 MAPT (0.71) MAPTSMN1; SMN2KDM4ERAB9AMEN1
SCHEMBL25327971 0.81 MAPT (0.71) MAPTSMN1; SMN2KDM4ERAB9AMEN1
SCHEMBL29478088 0.81 KDM4E (0.73) MAPTSMN1; SMN2KDM4ERAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4164891-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-04-19 EP disclosed
CN-115768631-A Fluorescent composition comprising at least one benzoxazole compound for protecting products 犯罪科学技术公司 2023-03-07 CN disclosed
CN-112239431-B Method for preparing 2-benzothiazole substituted aniline compound by catalysis of copper compound 广州大学 2022-05-13 CN disclosed