Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ILK | Q13418 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229456 | 0.88 | APP (0.68) | APPGAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28921709 | 0.86 | APP (0.57) | APPGAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL5423500 | 0.86 | TUBB4A (0.62) | APPKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL29657259 | 0.84 | MAPT (0.66) | APPKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL25329222 | 0.84 | MAPT (0.66) | APPKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL28313863 | 0.84 | APP (0.55) | APPCYP1A2CYP3A4CYP2C19ILK | |
| SCHEMBL28798406 | 0.83 | APP (0.61) | APPKDM4ENPC1GAAMAPT | |
| SCHEMBL27894269 | 0.83 | MAPT (0.56) | APPKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL17553302 | 0.82 | APP (0.60) | APPGAACYP1A2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL17541564 | 0.81 | APP (0.59) | APPGAACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112239431-B | Method for preparing 2-benzothiazole substituted aniline compound by catalysis of copper compound | 广州大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-102532055-B | Benzothiazole derivative compounds, composition and purposes | UNIV. OF PITTSBURGH OF THE COMMUNICATION SYSTEM OF HIGHER EDUCATION (US) | 2016-05-11 | — | — | CN | disclosed |
| CN-101355940-B | In vivo or in vitro method for detecting amyloid deposits having at least one amyloidogenic protein | UNIV PITTSBURGH | 2013-03-27 | — | — | CN | disclosed |
| CN-102973954-A | Amyloid imaging as a surrogate marker for efficacy of anti-amyloid therapies | UNIV PITTSBURGH | 2013-03-20 | — | — | CN | disclosed |