Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.80 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414341 | 1.00 | KDR (0.80) | KDRBCHERPS6KA3LRRK2FLT3 | |
| SCHEMBL28414342 | 1.00 | KDR (0.80) | KDRBCHERPS6KA3LRRK2FLT3 | |
| SCHEMBL29657615 | 0.91 | KDR (0.83) | KDRRPS6KA3LRRK2FLT3MEN1 | |
| SCHEMBL28415507 | 0.91 | KDR (0.83) | KDRRPS6KA3LRRK2FLT3MEN1 | |
| SCHEMBL28415508 | 0.91 | KDR (0.83) | KDRRPS6KA3LRRK2FLT3MEN1 | |
| SCHEMBL28414126 | 0.89 | KDR (1.00) | KDRRPS6KA3FLT3MEN1KMT2A | |
| SCHEMBL29657627 | 0.89 | KDR (1.00) | KDRRPS6KA3FLT3MEN1KMT2A | |
| SCHEMBL28414128 | 0.89 | KDR (1.00) | KDRRPS6KA3FLT3MEN1KMT2A | |
| SCHEMBL28890846 | 0.89 | KDR (0.74) | KDRBCHEFLT3MEN1KMT2A | |
| SCHEMBL28890847 | 0.89 | KDR (0.74) | KDRBCHEFLT3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153889-B | 2-indolone-triazole anti-tumor compound and preparation method and application thereof | 中国医科大学 | 2022-05-20 | — | — | CN | disclosed |