Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.56 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 4/20 | 0.39 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123248 | 1.00 | CD274 (0.56) | CD274PDCD1LG2OPRM1OPRD1MME | |
| SCHEMBL30011213 | 0.97 | PDCD1LG2 (0.54) | CD274PDCD1LG2OPRM1OPRD1MME | |
| SCHEMBL19734974 | 0.97 | PDCD1LG2 (0.54) | CD274PDCD1LG2OPRM1OPRD1MME | |
| SCHEMBL29572136 | 0.92 | CD274 (0.59) | CD274PDCD1LG2OPRM1OPRD1MME | |
| SCHEMBL29379448 | 0.92 | CD274 (0.59) | CD274PDCD1LG2OPRM1OPRD1MME | |
| SCHEMBL29571501 | 0.92 | CD274 (0.59) | CD274PDCD1LG2OPRM1OPRD1MME | |
| SCHEMBL31174311 | 0.92 | CD274 (0.59) | CD274PDCD1LG2OPRM1OPRD1MME | |
| SCHEMBL38663936 | 0.91 | OPRM1 (0.49) | CD274PDCD1LG2OPRM1OPRD1MME | |
| SCHEMBL31130576 | 0.90 | OPRM1 (0.48) | CD274PDCD1LG2OPRM1OPRD1MME | |
| SCHEMBL30931504 | 0.90 | PDCD1LG2 (0.53) | CD274PDCD1LG2OPRM1OPRD1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478789-A | anti-PD-L1 and OX40 bispecific antibodies and uses thereof | 安徽安科生物工程（集团）股份有限公司 | 2022-05-13 | — | — | CN | disclosed |