SCHEMBL29658174

SCHEMBL29658174

CC(C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 19/20 0.62
▸ SCTR P47872 1/20 0.62
▸ TFPI P10646 1/20 0.57
▸ GCGR P47871 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29622989 0.97 GLP1R (0.65) GLP1RSCTRTFPIGCGR
Histatin 5 SCHEMBL31694496 0.94 GLP1R (0.57) GLP1RSCTRTFPIGCGR
SCHEMBL31690552 0.92 GLP1R (0.61) GLP1RSCTRTFPIGCGR
SCHEMBL30538628 0.92 TFPI (0.68) GLP1RSCTRTFPIGCGR
SCHEMBL31683313 0.92 IL23R (0.59) GLP1RSCTR
SCHEMBL31005069 0.91 TFPI (0.64) GLP1RSCTRTFPIGCGR
SCHEMBL31690549 0.90 GLP1R (0.61) GLP1RSCTRTFPI
SCHEMBL30498856 0.90 GLP1R (0.68) GLP1RSCTR
SCHEMBL29670119 0.90 GLP1R (0.57) GLP1RSCTRTFPIGCGR
Histatin 3 SCHEMBL31694493 0.89 TFPI (0.63) GLP1RSCTRTFPIGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4654946-A1 LIPOSOMAL CONSTRUCT AC Immune SA (CH) 2025-12-03 — — EP disclosed
EP-4654990-A1 ANTI-ABETA VACCINE THERAPY AC Immune SA (CH) 2025-12-03 — — EP disclosed
WO-2024156912-A1 ANTI-ABETA VACCINE THERAPY AC IMMUNE SA (CH) 2024-08-02 — — WO disclosed
WO-2024156908-A1 LIPOSOMAL CONSTRUCT AC IMMUNE SA (CH) 2024-08-02 — — WO disclosed
US-20240252507-A1 SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF SOLENO THERAPEUTICS, INC. 2024-08-01 — — US disclosed
EP-3972633-A1 ANTI-ABETA VACCINE THERAPY AC Immune SA (CH) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240252507-A1 SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF KCNJ1, KCNJ11, KCNJ2 GLP1R 345/4885SCTR 2079/4885TFPI 3625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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