Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.67 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.65 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | BCL2 | P10415 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | IL1B | P01584 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19453139 | 1.00 | STAT3 (0.67) | STAT3CRBNDDB1CA2DYRK2 | |
| SCHEMBL29658250 | 1.00 | STAT3 (0.67) | STAT3CRBNDDB1CA2DYRK2 | |
| SCHEMBL20305742 | 1.00 | STAT3 (0.67) | STAT3CRBNDDB1CA2DYRK2 | |
| SCHEMBL30312821 | 1.00 | STAT3 (0.67) | STAT3CRBNDDB1CA2DYRK2 | |
| SCHEMBL19508771 | 1.00 | STAT3 (0.67) | STAT3CRBNDDB1CA2DYRK2 | |
| SCHEMBL19475751 | 1.00 | STAT3 (0.67) | STAT3CRBNDDB1CA2DYRK2 | |
| SCHEMBL19475684 | 0.99 | CRBN (0.66) | STAT3CRBNDDB1CA2DYRK2 | |
| SCHEMBL29362368 | 0.99 | CRBN (0.66) | STAT3CRBNDDB1CA2DYRK2 | |
| SCHEMBL26813299 | 0.98 | STAT3 (0.65) | STAT3CRBNDDB1CA2DYRK2 | |
| SCHEMBL26813160 | 0.97 | STAT3 (0.64) | STAT3CRBNDDB1CA2DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042762-A1 | MERTK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-02-12 | — | — | US | disclosed |
| EP-4613773-A2 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |
| EP-4522158-A2 | PAK1 DEGRADERS AND METHODS OF USE THEREOF | Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2024108009-A1 | DYRK/CLK PROTACS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-05-23 | — | — | WO | disclosed |
| EP-4334303-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | Nurix Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-4297792-A1 | COMPOUNDS FOR PROGRAMMABLE PROTEIN DEGRADATION AND METHODS OF USE FOR THE DISEASE TREATMENT | Mayo Foundation for Medical Education and Research (US) | 2024-01-03 | — | — | EP | disclosed |
| WO-2023220722-A2 | PAK1 DEGRADERS AND METHODS OF USE THEREOF | INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022237904-A1 | NAPHTHALENE RING-CONTAINING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-11-17 | — | — | WO | disclosed |
| WO-2022235715-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022183006-A1 | COMPOUNDS FOR PROGRAMMABLE PROTEIN DEGRADATION AND METHODS OF USE FOR THE DISEASE TREATMENT | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2022-09-01 | — | — | WO | disclosed |
| WO-2022098108-A1 | NLRP3 PROTEIN DEGRADATION INDUCING COMPOUND | (주) 업테라 | 2022-05-12 | — | — | WO | disclosed |
| EP-3972966-A1 | BCL-2 PROTEIN INHIBITORS | Recurium IP Holdings, LLC (US) | 2022-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042762-A1 | MERTK DEGRADERS AND USES THEREOF | MERTK, CRKL, OSTC | STAT3 4380/4885CRBN 39/4885DDB1 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.